The European Commission's Gender Equality Strategy 2020-2025 sets the current framework for EU action to promote one of its fundamental values, equality between women and men. The year 2021 was the second year of its implementation. It was also the second year of the COVID-19 pandemic, which clearly exposed the persistence of some deep-rooted inequalities in society and in the economy, while simultaneously recalling societys reliance on women and their work, and its continued undervaluation. This report takes stock of the main initiatives to promote equality between women and men in the past twelve months in the key areas of the Strategy: (1) being free from violence and stereotypes; (2) thriving in a gender-equal economy; (3) leading equally throughout society; (4) gender mainstreaming and funding; and (5) promoting gender equality and women's empowerment across the world. The report focuses on key actions and achievements on gender equality by EU institutions and Member States. It showcases some inspiring practices and innovative projects and presents key trends and the newest available data.